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* whole genome
* exome
* panel of genes
* mRNA-seq!
* ChIP-seq! ATAC-seq!
* patogeni organizmi ...
zamjena aminokiseline
u proteinu
točkasta
mutacija
fenotip
nanopore
pirosekvenciranje
H
O
Polymerase
H
Hydrogen
+
O
O
O
O
Pyrophosphate
P
O
O
4-
O
P
O
O
O
O
H
O
O
O
O
O
O
O
P
P
P
H
O
Polymerase
dNTP
Polymerase integrates a nucleotide.
Hydrogen and pyrophosphate are released.
sekvenciranje sintezom
(sequence by synthesis)
Sanger
sekvenciranje zaustavljanjem sinteze
(by chain termination)
bojom
ionsko
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home
phenotype
missense
nmd
proteasome
home2
fragments
seq
sanger
sintezom
nanopore
agenda
home3